Born in 1954 in Sweden, he graduated with a Soloists diploma at the Stockholm Royal College of Music in 1976 and continued his studies at the Liszt Academy of Music in Budapest. Mats has been a soloist with all the leading orchestras of Sweden, with conductors such as Gennady Rozhdestvensky, Myung-Whun Chung, Paavo Berglund and Leif Segerstam. His numerous solo recitals include all the solo pieces by Bach and Bartók's Solo sonata.
He was the leader of the Zetterqvist Quartet from 1974 to 2002 and the Zquartet until 2007. He was also leader of the Stockholm Radio Symphony Orchestra from 1989 to 1994.
He is a member of Trio Mats, a piano trio with an international reputation, alongside pianist Mats Widlund and cellist Mats Rondin.
Mats Zetterqvist has also appeared as a conductor in recent years with various chamber and symphony orchestras. In the new trio RoMA together with pianist Roland Pöntinen and percussionist Anders Loguin he performs music written for this ensemble by prominent contemporary composers. He is a Professor of Chamber Music at Edsberg High School of Music in Stockholm and a member of the Stockholm Royal Academy of Music.
He plays a 1768 Guadagnini violin.